نوع مقاله: مقاله کامل پژوهشی

نویسندگان

1 کارشناس ارشد مهندسی مکانیک- تبدیل انرژی، گروه مهندسی مکانیک، دانشگاه سیستان و بلوچستان

2 استادیار، گروه مهندسی مکانیک، دانشگاه سیستان و بلوچستان

3 دانشیار، دانشکده مهندسی پزشکی، دانشگاه صنعتی امیرکبیر (پلی تکنیک تهران)

4 استاد، بخش بافت شناسی، دانشگاه علوم پزشکی زاهدان

10.22041/ijbme.2013.13085

چکیده

در لایه های دیواره شریان بوده و این تجمع نیز متأثر از LDL پارامترهای جریان خون همواره متأثر از مکان و شکل تجمع ذرات جریان فیلتراسیون خون در لایه های دیواره شریان است. در این مقاله به منظور بررسی اثر انعطاف پذیری بر روی جریان فیلتراسیون در جریان ضربانی و غیر نیوتنی خون از یک شریان کاروتید با گرفتگی متقارن و با دیواره دو لایه ای انعطاف پذیر متخلخل، از مدل استفاده شده و نتایج آن با نتایج حاصله از مدل دیواره صلب و (PFSI) حل اجزای محدود همراه با برهمکنش سیال و جامد متخلخل مقایسه شده است. پارامترهای مورد مطالعه در این بررسی برای سه شدت گرفتگی متفاوت انجام شده (Porous Rigid متخلخل (مدل کاهش داشته است. Porous Rigid نسبت به مدل PFSI است. نتایج حاصل نشان می دهد که تنش برشی دیواره حدود 22 % در مدل در نواحی قبل و بعد از Porous Rigid نسبت به مدل PFSI همچنین سرعت فیلتراسیون در دیواره متخلخل شریان حاصله از مدل ناحیه گرفتگی، افزایش زیادی در حدود 20 % داشته است، ولی تفاوت سرعت فیلتراسیون بین دو مدل، در ناحیه گرفتگی شریان بسیار ناچیز بوده است.

کلیدواژه‌ها

موضوعات

عنوان مقاله [English]

Numerical investigation of the effects of wall flexibility on the infiltration parameters of a symmetric carotid artery stenosis with a two-layer hyperelastic structure

نویسندگان [English]

  • Saeed Nahidi 1
  • Alireza Hossein-Nezhad 2
  • Nasser Fatouraee 3
  • Zahra Heidari 4

1 Department of Mechanical Engineering, University of Sistan and Baluchestan

3 Biological Fluid Mechanics Research Laboratory, Biomedical Engineering Faculty, Amirkabir University of Technology

4 Division of Histology, Faculty of Medicine, Zahedan University of Medical Sciences

چکیده [English]

Blood flow parameters are affected by position and shape of the accumulation of low density lipoprotein (LDL) in the layers of the arterial wall, and this phenomenon itself is influenced by infiltration flow of the blood. In this paper, in order to investigate the effect of wall flexibility on the infiltration flow in a pulsatile non-Newtonian blood flow in a symmetric carotid artery stenosis with a two flexible and porous layers, a finite element model with Porous Fluid Structure Interaction (PFSI) method was used and the results were compared to the porous rigid model. Study parameters were investigated in three different stenosis severities. Comparison of the presented results using PFSI model with those of Porous Rigid model showed about 22% decrease in wall shear stress in the stenosis region, about 20% increase in filtration velocity in the pre- and post-stenosis regions of the porous layer, but a slight difference in filtration velocity in the stenosis region.

کلیدواژه‌ها [English]

  • Porous Fluid Structure Interaction
  • infiltration flow
  • pore pressure
  • Pulsatile Flow
  • non-Newtonian blood
  • two-layer porous hyperelastic

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