نوع مقاله: مقاله کامل پژوهشی

نویسندگان

1 استادیار دانشکده مهندسی مکانیک، دانشگاه صنعتی نوشیروانی

2 استاد دانشکده مهندسی پزشکی، دانشگاه صنعتی امیرکبیر

3 استادیار دانشکده مهندسی پزشکی، دانشگاه صنعتی امیرکبیر

4 استادیار پژوهشکده سرامیک، پژوهشگاه مواد و انرژی

10.22041/ijbme.2007.13490

چکیده

در این تحقیق اثر غلظت های مختلف NaH2PO4.2H2O بر زمان گیرش و استحکام فشاری سیمان استخوانی بر پایه هیدروکسی آپاتیت بررسی شد. سیمان هیدروکسی آپاتیت دسته ای از سیمان های استخوانی کلسیم فسفاتی است که می تواند به عنوان جایگزین بافتهای سخت مطرح شود. قسمت پودری این سیمان از ترکیبات مختلف کلسیم فسفاتی نظیر تری کلسیم فسفات (TCP)، کربنات کلسیم (CaCO3) و مونتیت (CaHPO4) تهیه شد و فاز مایع آن نیز غلظت های مختلفی از سدیم دی هیدرژن فسفات را شامل گردید. زمان های گیرش اولیه و نهایی و استحکام فشاری سیمان در نسبت های مختلفی از فاز مایع به جامد L/P(ml/g) بررسی شد. نتایج به دست آمده بیانگر آن است که در غلظت های معینی از فاز مایع، این سیمان از شرایط بالقوه ای برای کاربردهای پزشکی برخوردار است.

کلیدواژه‌ها

موضوعات

عنوان مقاله [English]

Effect Of Liquid Phase Concentration On Setting Time And Compression Strength Of Hydroxyapatite Bone Cement

نویسندگان [English]

  • Seyed Mahmoud Rabiei 1
  • Fathollah Moztarzadeh 2
  • Mehran Solati Hashjin 3
  • Saeed Hesaraki 4

1 Assistant professor, Mechanical Engineering School, Babol Noshirvani University of Technology

2 Professor, Biomedical Engineering School, Amirkabir University of Technology

3 Assistant Professor, Biomedical Engineering School, Amirkabir University of Technology

4 Assistant Professor, Department of Ceramics, Material and Energy Research Center

چکیده [English]

In this research, the influence of NaH2PO4.2H2O with different concentrations on setting time and compressive strength of bone cement based on hydroxyapatite was investigated. Hydroxyapatite cement is of calcium phosphate bone cements, which can be considered as the best substitute for hard tissues. The powder phase of the cement was prepared from various compositions of calcium phosphates such: tricalcium phosphate (TCP), calcium carbonate (CaCO3) and montite (CaHPO4) as constant and the liquid part using NaH2PO4.2H2O solution with different concentrations. The influences of liquid/powder ratio L/P (ml/g) was investigated on the initial and final setting times and compressive strengths of the cement. According to the obtained results, with optimum concentrations of the liquid phase, this cement seems suitable for clinical applications.

کلیدواژه‌ها [English]

  • Bone tissue engineering
  • Bone Cement
  • Hydroxyapatite
  • Nah2po4.2h2o
  • Setting Times
  • Compressive strength

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