TY - JOUR
ID - 13489
TI - Determination Of Elastic Modulus Of Artery Wall By Modeling Of Artery Wall And Blood Flow
JO - Iranian Journal of Biomedical Engineering
JA - IJBME
LA - en
SN - 5869-2008
AU - Maerefat, Mehdi
AU - Khoushkar Shalmani, Asghar
AU - Mokhtari Dizaji, Manije
AD - Associate professor, Mechanics Department, Engineering School, Tarbiat Modares University
AD - MS Mechanical Engineer, Engineering School, Tarbiat Modares University
AD - Associate professor, Medical Physics Department, Medical School, Tarbiat Modares University
Y1 - 2007
PY - 2007
VL - 1
IS - 2
SP - 95
EP - 104
KW - elastic modulus
KW - Blood pressure
KW - Pulsatile Flow
KW - Ultrasound
KW - Coupled Fluid/Solid Model
DO - 10.22041/ijbme.2007.13489
N2 - Modeling of blood flow and arterial wall in large arteries such as carotid artery, using ultrasonic measurements, allows non-invasive evaluation of clinically interesting homodynamic variables. In this study, a nonlinear mathematical model for the pulsatile arterial flow is proposed using the approximation of “local flow” theory. The blood velocity profile, the pressure gradient and the elastic modulus can be calculated using the model by measuring instantaneous radius and center-line blood velocity. An original mathematical model of pressure gradient in a tapered and elastic tube, using center-line blood velocity, is presented. A Newtonian incompressible Navier-Stokes solver coupled with elastic or visco-elastic arterial wall model is developed to solve the equations of model. The results of modeling and simulation indicate that the approach can estimate the elastic modulus of arterial wall from ultrasonic data. There is a good agreement between the computed arterial wall elasticity and the measured one. The method presented is relatively simple to implement clinically and can be taken as a new diagnostic tool for detecting local vascular change.
UR - https://www.ijbme.org/article_13489.html
L1 - https://www.ijbme.org/article_13489_2b9b93b9daf078dbcc86e6c44d57320b.pdf
ER -