Full Research Paper
Fluid-Structure Interaction in Biological Media / FSI
Alireza Hashemi Fard; Nasser Fatouraee
Volume 5, Issue 1 , June 2011, Pages 1-12
Abstract
The heart muscle is supplied via the coronary arteries. The coronary arteries are deformed in each cardiac cycle by the contraction of the myocardium. The aim of this work was to investigate the effects of physiologically idealized cardiac-induced motion on flow rate in human left coronary arteries. ...
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The heart muscle is supplied via the coronary arteries. The coronary arteries are deformed in each cardiac cycle by the contraction of the myocardium. The aim of this work was to investigate the effects of physiologically idealized cardiac-induced motion on flow rate in human left coronary arteries. The blood flow rate were numerically simulated in an elastic modeled left anterior descending coronary artery (LAD) having a uniform circular cross section. Blood was considered to be a non-Newtonian fluid and Arterial motion was specified based on monoplane physiologically idealized bending. Simulations were carried out with dynamic pressure difference conditions between inlet and outlet in both fixed and moving LAD models, to evaluate the relative importance of LAD motion, flow rate, and the interaction between motion and time-averaged flow rate. LAD motion was caused variations in time-averaged flow rate in the moving LAD models as compare as the fixed models. There was significant variability in the magnitude of this motion-induced flow variation. However, the magnification of time-averaged flow rate is depending to specification of the cardiac motion. Furthermore, the effects of pressure pulsatility dominated LAD motion induced effects; specifically, there were local flow variation and secondary flow in the simulations conducted in moving LAD models.
Full Research Paper
Biomechanics of Bone / Bone Biomechanics
Mohammad Mehdi Khani; Mohammad Tafazzoli Shadpour; Farzane Aghajani; Peyman Naderi
Volume 5, Issue 1 , June 2011, Pages 13-20
Abstract
Stress analysis is a proper tool in evaluation of vulnerable regions of dental tissues exposed to cyclic loading due to mastication and other physiological functions. In this study, effects of visco-elastic property of dental components on the distribution of stress are investigated in finite element ...
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Stress analysis is a proper tool in evaluation of vulnerable regions of dental tissues exposed to cyclic loading due to mastication and other physiological functions. In this study, effects of visco-elastic property of dental components on the distribution of stress are investigated in finite element models of upper central tooth prone to dynamic loading. Sensitivity of stress pulse to the visco-elastic property is studied. Results indicate reduction of stress pulse amplitude by elevation of visco-elastic parameter with highest effect in enamel-cementum junction and then in enamel-dentin junction. The visco-elastic property causes smoothening of the stress distribution in dental tissues. Such effect is due to reduction of stress wave amplitude and elevation of the ratio of minimum to maximum stress values. Increased visco-elasticity of components results in elevated phase shift between load and stress waves and higher attenuation of stress wave. This causes slow propagation of attenuated wave leading to lower maximum stress after reflection of stress wave in boundaries and junctions.
Full Research Paper
Biomechanics of Bone / Bone Biomechanics
Mohammad Nikkhoo; Mohammad Haghpanahi; J. L. Wang; Mohammad Parnianpour
Volume 5, Issue 1 , June 2011, Pages 21-32
Abstract
Prediction of the relationship between different types of mechanical loading and the failure of the intervertebral disc is so important to identify the risk factors which are difficult to study in vivo and in vitro. On the basis of finite element methods some of these issues may be overcome ...
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Prediction of the relationship between different types of mechanical loading and the failure of the intervertebral disc is so important to identify the risk factors which are difficult to study in vivo and in vitro. On the basis of finite element methods some of these issues may be overcome enabling more detailed assessment of the biomechanical behavior of the intervertebral disc. The objective of this paper is to develop a nonlinear axisymmetric poroelastic finite element model of lumbar motion segment and show its capability for studying the time-dependent response of disc. After comparison of the response of different models in quasi-static analysis, the poroelastic model of intervertebral disc is presented and the results of short-term, long-term creep tests and cyclic loading were investigated. The results of the poroelastic model are in agreement with experimental ones reported in the literature. Hence, this model can be used to study how different dynamic loading regimes are important as risk factors for initiation of intervertebral disc degeneration.
Full Research Paper
Biomechanics of Bone / Bone Biomechanics
Behnoud Haghighi; Masoud Tahani; Gholam Reza Rouhi
Volume 5, Issue 1 , June 2011, Pages 33-44
Abstract
Orthopedic screws are widely used devices for fixation of bone fractures. Progressive loosening of bone fixation screws, induced by stress shielding and subsequent adaptive bone remodeling, results in bone loss around the screw. A set of two-dimensional finite element models including cortical and cancellous ...
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Orthopedic screws are widely used devices for fixation of bone fractures. Progressive loosening of bone fixation screws, induced by stress shielding and subsequent adaptive bone remodeling, results in bone loss around the screw. A set of two-dimensional finite element models including cortical and cancellous bone with a functionally graded Ti-Hap screw was developed. A dimensionless set of stress-transfer parameters (STP) and strain energy density-transfer parameter (SEDTP) were developed to quantify the screw–bone load sharing. Lower STP and SEDTP values indicate weak stress and strain energy density transfer to bone which is a sign of stress shielding. The results indicated that STP and SEDTP values for FGM screw are higher than those of a fully metal screw. Moreover, reducing elastic modulus of metal fraction and increasing the volume fraction of ceramic decrease the stress shielding. For a partially graded screw (with both homogenous and FGM parts), the longer FGM part is, the greater are STP and SEDTP values. Furthermore, the results showed that decreasing compositional distribution exponent which shows composition change of FGM content from metal fraction toward ceramic fraction, increases the parameters. Results from this study are in admissible agreement with available clinical and experimental study.
Full Research Paper
Fluid-Structure Interaction in Biological Media / FSI
Borhan Alhoseini Hamedani; Mehdi Navidbakhsh; Hosein Ahmaditafti
Volume 5, Issue 1 , June 2011, Pages 45-56
Abstract
In this paper, study of mechanical properties of human blood vessels is considered, especially those of related to the Coronary Artery Bypass Graft (CABG). Unfortunately more than 30% of saphenous grafts are re-occluded within 10 years while mammary artery shows better results. In this study elastomechanical ...
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In this paper, study of mechanical properties of human blood vessels is considered, especially those of related to the Coronary Artery Bypass Graft (CABG). Unfortunately more than 30% of saphenous grafts are re-occluded within 10 years while mammary artery shows better results. In this study elastomechanical properties of human saphenous vein, which is common in CABG, is studied. Stress-stretch behavior of these samples after a cyclic loading was obtained and large deformation formulation was used to obtain real stress and stretch ratio of these vessels. Then a fourth order polynomial was used to show nonlinear behavior of these results. Results show that blood vessel stiffness in longitudinal direction is two times greater than circumferential direction, while it is more than 74% stretchable in the circumferential direction. So modulus of elasticity in longitudinal direction is greater than circumferential direction. If we continue stretching until final rupture after maximum strength, longitudinal samples will be broken down faster than circumferential samples because of collagen fibers orientation.
Full Research Paper
Bioheat Transfer
Mohammad Shams Kolahi; Ataollah Hashemi
Volume 5, Issue 1 , June 2011, Pages 57-66
Abstract
Recent technological and industrial advances have increased the number of skin burns due to human body exposure to heat in a fire or hot and mechanized environment. In addition, hot environment can produce a strain on a human body leading to discomfort and heat stress and even death. In hot summer days, ...
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Recent technological and industrial advances have increased the number of skin burns due to human body exposure to heat in a fire or hot and mechanized environment. In addition, hot environment can produce a strain on a human body leading to discomfort and heat stress and even death. In hot summer days, many people suffer from heat stroke, dehydration and loss of body fluid. Therefore, the subject of studying thermal energy transport in living tissues is useful for assessing skin burns accurately, better understanding the thermoregulatory system of the body and for developing thermal protection standards. In a hot environment, the most important factor to control the body temperature is evaporation. Accordingly, this study solves one dimensional Pennes’ bio-heat equation by means of backward finite difference formulation. Physical and physiological factors taken into account are: sweat secretion, capillary blood circulation (perfusion), metabolic heat, heat and water exchange with the environment through convection and evaporation. Initially, the model is validated using the work of Zhao et al. Then, the evaporation term is added to the model to study the effect of ambient temperature variation on skin tissue temperature. The results show that thermal disease such as hyperthermia can be expected if uncovered skin is held for a specific time at hot environment. It is observed that increasing ambient temperature causes a shift in the location of the maximum temperature toward the surface of the skin, i.e., the maximum temperature occurs at the depth of about 9 and 7.6 mm of skin surface for ambient temperature of 50 and 60°C, respectively.
Full Research Paper
Fluid-Structure Interaction in Biological Media / FSI
Hamed Khalesi; Hanie Niroomand Oscuii; Farzan Ghalichi
Volume 5, Issue 1 , June 2011, Pages 67-78
Abstract
Biomechanics believe that, the arteries are remodeled under the influence of hemodynamic and mechanical factors. Biomechanical factors such as Opening Angle and the Tethering could have important effects on this phenomenon. The effects of various Opening Angle and Tethering during thoracic aorta aging ...
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Biomechanics believe that, the arteries are remodeled under the influence of hemodynamic and mechanical factors. Biomechanical factors such as Opening Angle and the Tethering could have important effects on this phenomenon. The effects of various Opening Angle and Tethering during thoracic aorta aging on arterial wall stress have been studied. ADINA software is used for numerical simulation.In this study, for the first time, numerical methods of Fluid-Structure Interaction have been used to study and simulate effects of Opening Angle and the Tethering in elastic artery remodeling due to age. Large deformation theory has been used for modeling changes of arterial radius; furthermore, behavior of Newtonian fluid has been used for blood. Pulsatile pressure and physiological Pulsatile flow waveforms have been applied to simulate transient behavior of arterial system. The results show that opening angle has further effect on circumferential stress so smooth distribution of circumferential stress on the wall accrued. Also, increasing Opening Angle with age reverses the circumferential stress distribution slop across the arterial wall. Tethering has further effect on axial stress. Decreasing Tethering in remodeling process over age leads to increase stress levels in the aged artery. Also, arterial wall shear stress in remodeled artery shows significant reduction in maximum, mean and amplitude values that caused reduction of pathological effects of endothelial cells.
