Document Type : Full Research Paper

Authors

• Gelare Valizadeh ¹
• Fateme Fatemi ¹
• Mahmoud Shahabadi ²
• Mohammad Ali Oghabian ³
• Majid Pouladian ⁴

¹ Research Center for Science and Technology in Medicine, Faculty of Engineering, science and research branch, Islamic Azad University, Tehran, Iran

² School of Electrical and Computer Engineering, College of Engineering, Tehran University, Tehran, Iran

³ Research Center for Science and Technology in Medicine, Faculty of Medical Physics, Tehran University, Tehran, Iran

⁴ Faculty of Engineering, science and research branch, Islamic Azad University, Tehran, Iran

Abstract

MTDDS is an innovative treatment modality to completely tumor remission with no negative side effect. In this method functionalize magnetic nanoparticles are designed as the drug carrier to get the specific target in the body. Anticancer agents are bounded to magnetite nanoparticles with biocompatible starch coating suspended in the fluid. Now if they are injected intra-arterially near the target volume, they would be trapped at the target region via a local applied magnetic field with the high gradient near the target site. In this paper we have evaluated some nanoparticle trajectories with different size in order to evaluate the effect of the size on the efficiency of the magnetic drug targeting system.

Keywords

• Magnetic drug delivery
• Nanoparticle
• Iron oxide
• COMSOL
• Particle

Main Subjects

• Biological Computer Modeling / Biological Computer Simulation