Document Type : Full Research Paper

Authors

Medical Physics Department, Faculty of Medicine, Tehran University, Tehran, Lran

10.22041/ijbme.2014.13046

Abstract

Detection of tumors at an early stage is important for the diagnosis of cancer. Therefore, to detect cancer cells it is necessary to distinguish between metastases from normal cells at an early stage. Due to the large size and coverage necessary to prevent chemical reactions of the current contrast agents in the body, they are just applicable to the extracellular space. Due to the small size of nanoparticles in comparison to cells, it is possible for them to enter the cells. Therefore, these materials are used for molecular imaging. In this paper, variations in the external magnetic field (Tesla) due to magnetic nanoparticles in homogeneous tissue were studied by the finite element method. For this purpose, a simulation was performed in the presence of magnetic nanoparticles and without it. By the finite element method, conversion of differential and integral governing equations to simple and solvable equations that are numerically stable was made possible. The results obtained indicate that the external magnetic field is intensified by the presence of magnetic nanoparticles.

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[1]     J. Jin, “The Finite Element Method in Electromagnetics” Jhon Wiley and Sons, second edition pp.1-15, 2002.
[2]     ABMA Hossain, M. Cho, S. Lee, “Magnetic nanoparticle density mapping from the magnetically induced displacement data” BioMedical Engineering 2012.
[3]     C. Sprouse, “Equipment Design for Magnetic Nanoparticle Treatment”.
[4]     A. Barchanski, “Simulations of low-frequency electromagnetic fields in the human body” TU Darmstadt 2007.
[5]     P. K. Tiwari, S. K. Kang, G. J. Kim, et al. “Modeling of Nanoparticle-Mediated Electric Field Enhancement Inside Biological Cells Exposed to AC Electric Fields” Japanese Journal of Applied Physics 48 (8): 087001, 2009.
[6]     G. Wimmer, M. Clemens, J. Lang, “calculation of magnetic field with Finite Element”