Document Type : Full Research Paper


1 M.Sc Graduated, Biomedical Engineering Group, Electrical Engineering School, Sharif University of Technology

2 Assistant Professor, Biomedical Engineering Group, Electrical Engineering School, Sharif University of Technology



In this paper, an MRI-based diagnosing approach has been proposed which simultaneously analyzes T1-MR and T2-MR images. The dataset contains 120 cross-sectional images of abnormal and also normal brains as control group. Due to inherent proprieties of T1 and T2 images and their principal differences, particular features have been extracted from each image. Then, more meaningful data has been structured by automatically eliminating redundant data and generating a semi-linear combination of the remaining features. Considering the fact that Alzheimer's disease mainly damages the gray and white matter of the brain and knowing that these parts of the brain can be more clearly observed in T1 images, the classifier which works under a nonlinear structure, allocates more weight for processing the T1 images comparing to T2 image. The images, after being registered, have been processed in two groups of training and test sets. According to the results, three forth of the dataset which was obtained from Harvard University's dataset (The Whole Brain Atlas) has been correctly diagnosed.


Main Subjects

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