Triphasic Finite Element Modeling of Intervertebral Discs for Biomechanical Studies in Tissue Engineering

Haghpanahi, Mohammad; Nikkhoo, Mohammad; Peirovi, Habibollah

doi:10.22041/ijbme.2008.13458

Document Type : Full Research Paper

Authors

¹ Associate Professor, Biomechanics Research Lab, Mechanical Engineering School, Iran University of Science and Technology

² PhD Candidate, Biomechanics Research Lab, Mechanical Engineering School, Iran University of Science and Technology

³ Nonomedicine and Tissue Engineering Research Center, Shahid Beheshti University of Medical Science and Health Services

10.22041/ijbme.2008.13458

Abstract

According to mechanobilogical studies as an infrastructure for tissue engineering researches, this paper presents a triphasic finite element modeling of intervertebral discs such a hydrated porous soft tissue. First, the governmental equations were derived on the basis of the laws of continuum mechanics. Then the standard Galerkin weighted residual method was used to form the finite element model. The implicit time integration schemes were applied to solve the nonlinear equations. The formulation accuracy and convergence for one dimensional case were examined with Simon's and Sun's analytical solutions and also Drost's experimental Data. It was shown that the mathematical model is in excellent agreement and has the capability to simulate the intervertebral disc response under different types of mechanical and electrochemical loading conditions. Finally, to have a short review of the capability of the model, a homogenous two dimensional version of the model was applied to simulate the response of a simple sagittal slice of the intervertebral disc.

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Main Subjects

References

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Iranian Journal of Biomedical Engineering

Triphasic Finite Element Modeling of Intervertebral Discs for Biomechanical Studies in Tissue Engineering

References

References

Volume 2, Issue 1 - Serial Number 1
June 2008
Pages 47-56

Triphasic Finite Element Modeling of Intervertebral Discs for Biomechanical Studies in Tissue Engineering

References

References

Volume 2, Issue 1 - Serial Number 1June 2008Pages 47-56

Volume 2, Issue 1 - Serial Number 1
June 2008
Pages 47-56