Document Type : Full Research Paper


1 Associate Professor, Biomechanics Group, Mechanical Engineering School, Sahand University of Technology

2 Instructor, Biomechanics Group, Mechanical Engineering School, Sahand University of Technology

3 Associate Professor, Medical Engineering Group, Chemical Engineering School, Sharif University of Technology



In order to compare the aorta-coronary and coronary-coronary bypasses blood flow fields in the Endto-Side Anastomosis, we carried out numerical simulation of three dimensional pulsatile blood flow for 50% stenosis by using FLUENT 5.2.3 software. In this study, the blood was assumed to be as the Newtonian, incompressible and homogeneous fluid. The arterial wall was also considered to be rigid. Non-existence of the secondary flows in the coronary-coronary bypass blood flow fields for various degrees of bypass grafting angles against the aorta-coronary-coronary bypass, return of total blood flow toward upstream in the coronary-coronary bypass three times over a heart cycle, high temporary oscillation in the wall shear stress magnitudes for the aorta-coronary bypass and low wall shear stress magnitudes for the coronary-coronary bypass were of the important results.


Main Subjects

[1]     Nerem R. M., Levesque M. J., " Fluid Mechanics in Atherosclerosis", Handbook of Bioengineering (Edited by Skalak, R., Chein, S. Chap. 21, 1987, McGraw-Hill, New York.
[2]     Ethier C. R., Steinman D. A., Zhang X., “Flow Waveform Effects on End-to-Side Anastomosis Flow Patterns”, J. Biomechanics 1998; 31: 609-617.
[3]     Inzoli F, Migliavacca F and Pennati G, “Numerical Analysis of Steady Flow in Aorto-Coronary Bypass 3- D Model”, J. of Biomechanical Eng., 1996: 18.
[4]     Pietrabissa R., Inzoli F., Fumero R., “Simulation Study of Fluid Dynamics of Aorto-Coronary Bypass”, J. Biomed. Eng., 1990; 12: 419-424.
[5]     Fei D., Thomas J. D., Rittgers S. E., “The Effect of Angle and Flow Rate upon Hemodynamics in Distal Vascular Graft Anastomoses: A Numerical Model Study”, J. Biomechanical Eng., 1994; 116: 331-336.
[6]     Hughes P. E., How T. V., “Effect of Geometry and Flow Division on Flow Structures in Models of the Distal End-to-Side Anastomosis”, J. Biomechanics, 1996; 29(7): 855-872.
[7]     Ghalichi F., "Pulsatile Laminar and Turbulent Blood Flow Simulation in Large Stenosed Arteries and Stenosed Carotid Artery Bifurcation", PhD Thesis, Laval University, Quebec, Canada, 1998.
[8]     Kleinstreuer C et al.; Flow Input Waveform Effects on the Temporal and Spatial Wall Shear Stress Gradients in a Femoral Graft-Artery Connector", Transaction of the ASME, 1996; 118.
[9]     Ahmadlouydarab M., Ramazani A., Ghalichi F., “Simulation of Three Dimensional Pulsatile Blood Flow in Aorta-Coronary Bypass”, ICBME2004, Paper code: 305, p 72, Tehran - Iran, Feb. 2004.
[10] Boughner DR, Roach MR; Effect of Low Frequency Vibration on the Arterial Wall; Circ Res 1971; 29: 136-144.
[11] Cassanova RA, Giddens DP; Disorder Distal to Modeled Stenoses in Steady and Pulsatile flow; J Biomech 1978; 11: 441 453.
[12] Fluent User’s Guide Manuals, Vol. 2, Chapter 8.