Iranian Journal of Biomedical Engineering (IJBME)
نشریه علمی مهندسی پزشکی زیستی

Modeling Parkinsonian Gait and Investigating some Approaches to Increase the Gait Speed

Document Type : Full Research Paper

Authors

Seyede Fatemeh Ghoreishian Amiri 1
Mohammad Pooyan 2

1 M.Sc., Department of Biomedical Engineering, Faculty of Engineering, Shahed University, Tehran, Iran

2 Associate Professor, Department of Biomedical Engineering, Faculty of Engineering, Shahed University, Tehran, Iran

https://doi.org/10.22041/ijbme.2021.135873.1621
Abstract
Parkinson's disease (PD) is a neurological disorder that mainly affects dopamine-producing neurons and motor system. The most obvious symptoms of PD are tremor, slow movement, stiffness and difficulty with walking. Walking in PD is slower than normal walking. In this paper, the gait in patients with PD is modeled by a mathematical and computational method. This model includes structures which are involved in PD, such as basal ganglia, thalamus, cortex, supplementary motor area (SMA), muscle and joint-load dynamics. The output of the model is walking speed in PD. The output value is 0.83 m/s, which is in the range reported by clinical results (0.18-1.21 m/s). Some methods which increase the gait speed in PD are investigated too. These methods include deep brain stimulation, drug prescription and strengthening the muscles. The results show that each of these methods will improve the gait speed, in fact, by using these methods, the value of output increases and approaches the walking speed range in healthy individuals (1.36-1.30 m/s). Moreover, the effect of rigidity on gait speed is studied; it has been observed that the stiffness and speed of the gait are inversely related. Finally a control method is offered which improve the gait speed by increasing the magnitude response of the closed-loop system.

Keywords

Parkinson’s Disease
Modeling
Gait Speed
Improving
Subjects
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Iranian Journal of Biomedical Engineering (IJBME)
Volume 14, Issue 4
Winter 2021
Pages 321-331

  • Receive Date 04 September 2020
  • Revise Date 30 December 2020
  • Accept Date 12 January 2021

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