Analysis of Feedback Effect on the Neural Sources of P300 Component

Sabeti, Malihe; Boostani, Reza; Moradi, Ehsan

doi:10.22041/ijbme.2019.104838.1457

Document Type : Full Research Paper

Authors

¹ Assistant Professor, Computer Engineering Department, North Tehran Branch, Islamic Azad University, Tehran, Iran

² Associate Professor, CSE & IT Department, Faculty of Electrical and Computer Engineering, Shiraz University, Shiraz, Iran

³ Assistant Professor, Department of Neurosurgery, Mofid Children’s Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran

https://doi.org/10.22041/ijbme.2019.104838.1457

Abstract

The P300 event-related potentials (ERPs) has implicated in outcome evaluation and reward processing. It is controversial how reward processing affects the neural sources of P300. We try to investigate the effect of feedback on the neural sources of P300 component. Thirty healthy subjects were participated and their EEG signals were recorded by thirty channels through the start (30 minutes), feedback (60-90 minutes) and last (30 minutes) segments. We analyzed feedback segment where an equal number of audio and visual stimulus were applied to the participants to perform audio and visual recognition tasks. We punished participants for wrong answers where each wrong answer adds four more tests to this segment. The P300 component was extracted from the background EEG at all channels using the conventional time-locked synchronous grand averaging over all time frames and subjects. Next, two well-known source localization algorithms including standardize low resolution electromagnetic tomography (sLORETA) and shrinking sLORETA were applied to the P300 waveforms for estimating the activity of the P300 sources. Our finding show a significant increase in the activation of P300 sources in the feedback-locked compared to the stimulus-locked over right tempo-parieto-occipital areas (secondary association area) in visual recognition task, but difference of P300 sources is not significant in audio recognition task. The discrepancy between the audio and visual task confirms the hypothesis that our participants considered more probability of wrong answers in the audio task, but they respond to visual test with more confidence.

Keywords

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Iranian Journal of Biomedical Engineering

Analysis of Feedback Effect on the Neural Sources of P300 Component

References

References

Volume 13, Issue 4
December 2019
Pages 291-301

Analysis of Feedback Effect on the Neural Sources of P300 Component

References

References

Volume 13, Issue 4December 2019Pages 291-301

Volume 13, Issue 4
December 2019
Pages 291-301