نوع مقاله: مقاله کامل پژوهشی

نویسندگان

1 دانشجوی کارشناسی ارشد مهندسی پزشکی، گروه بیومکانیک، دانشکده‌ی مهندسی پزشکی، دانشگاه صنعتی سهند تبریز، تبریز، ایران

2 دانشیار، گروه بیومکانیک، دانشکده‌ی مهندسی پزشکی، دانشگاه صنعتی سهند تبریز، تبریز، ایران

3 دانشجوی دکتری، دانشکده‌ی مهندسی پزشکی،دانشگاه صنعتی سهند تبریز، تبریز، ایران

چکیده

امروزه با پیش‌رفت تکنولوژی و زندگی ماشینی، تعداد مبتلایان به بیماری‌های قلبی در حال افزایش است. از طرفی تعداد قلب­های آماده‌ی پیوند در دنیا محدود می‌باشد. بنابراین استفاده از پمپ­های قلبی برای کمک به بیمار در طول زمان انتظار و حتی تا آخر عمر، جای‌گزین مناسبی به شمار می‌رود. پمپ­های کمکی قلب باید توانایی برآورده کردن نیاز­های بیولوژیکی مانند فشار و دبی مناسب قلب را داشته باشند و هم‌چنین از نظر آسیب­های خونی در ناحیه‌ی امن قرار گیرند. از چالش­های مهم در طراحی پمپ­های کمک قلبی می­توان به کوچک کردن ابعاد پمپ، کاهش زمان ماندگاری خون در داخل پمپ و کاهش آسیب­های خونی مانند خون‌کافت اشاره کرد. در 30% از بیمارانی که تحت عمل جراحی جای‌گذاری پمپ کمکی بطن چپ قرار گرفته‌اند، پس از مدتی بطن راست آن‌ها نیز دچار نارسایی شده و به پمپ کمکی بطن راست نیاز بیدا کرده‌اند. از جمله محدودیت­های فیزولوژیکی برای جریان ریوی، تولید فشار 15-25 میلی‌متر جیوه و دبی 5 لیتر بر دقیقه می‌باشد. شایان ذکر است که تولید فشار بیش از 25 میلی‌متر جیوه منجر به ایجاد فشار خون در شریان ریوی و مشکلات متاثر از آن خواهد شد. در این پژوهش یک پمپ قلبی گریز از مرکز با تمرکز روی هندسه‌ی پره برای بطن راست طراحی شده است. این پمپ با استفاده از دینامیک سیالات محاسباتی برای سرعت­های دورانی 1500 و 2000 دور در دقیقه و دبی‌های 4-6 لیتر بر دقیقه شبیه‌سازی شده است. پمپ طراحی شده، دبی 5 لیتر بر دقیقه در سرعت دورانی 1500 دور در دقیقه و فشار 23 میلی‌متر جیوه را تولید می­کند. میزان شاخص خون‌کافت محاسبه شده با استفاده از روش لاگرانژی برابر با 00413/0 است.

کلیدواژه‌ها

عنوان مقاله [English]

Design and Simulation of the Right Ventricular Mini Assist Centrifugal Pump

نویسندگان [English]

  • Reza Sahebi Kuzeh Kanan 1
  • Hanieh Niroomand-Oscuii 2
  • Kohyar Yazdanpanah-Ardakani 3

1 M.Sc. Student, Department of Biomedical Engineering, Sahand University of Technology, Tabriz, Iran

2 Associate Professor, Department of Biomedical Engineering, Sahand University of Technology, Tabriz, Iran

3 Ph.D. Student, Department of Biomedical Engineering, Sahand University of Technology, Tabriz, Iran

چکیده [English]

Nowadays, patients crowd suffering from heart disease are increasing along with the development of technology and mechanized life. On the other hand, donor hearts ready for transplantation is limited in the world. Therefore, exploiting blood pumps is a suitable alternative for helping the patient during the waiting time and even until the end of life. The blood pumps should be able to satisfy the biological needs, including proper output pressure and flow rate, in an acceptable margin of safety in terms of blood injuries. Reduction of pump size, blood exposure time and blood damages such as hemolysis are mentioned as the important challenges in the design of blood pumps. 30% of the patients who are using a left ventricle blood pump, required right ventricle blood pump due to right ventricle failure. Fulfilling the physiological requirement of right ventricle a RVAD must generate pressure in the range of 15-25 mmHg and flow rate equal to 5 L/min. generation of pressure over 25 mmHg will lead to pulmonary hypertension and its consequent problems. In this research, a centrifugal blood pump is designed for the right ventricle with an emphasis on impeller geometry. This pump is simulated for rotational speeds of 1500, 2000 rpm and flow rates of 4-6 L/min by using the computational fluid dynamics. The designed pump produces a flow rate of 5 L/min at 1500 rpm and a pressure of 23 mmHg. The amount of the hemolysis index calculated by the Lagrangian method is 0.00413.

کلیدواژه‌ها [English]

  • Heart
  • Ventricular Assist Device
  • impeller
  • hemolysis
  • centrifugal pump

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