Physicochemical Properties And Cellular Responses Of Various Amounts Of Strontium-Doped Gypsum Bio Ceramics

Bandegani, Hadis; Hesaraki, Saeed; Alizadeh, Masoud

doi:10.22041/ijbme.2009.13390

Document Type : Full Research Paper

Authors

¹ M.Sc Student of Materials Engineering, Ceramics Department, Materials and Energy Research Center

² Assistant Professor, Ceramics Department, Materials and Energy Research Center

10.22041/ijbme.2009.13390

Abstract

The aim of the present paper is to investigate the effect of incorporating various amounts of strontium ions (0.19 - 2.23 wt%) into calcium sulfate bio ceramics on the physical, structural properties and in vitro bioactivity and compare these properties with those of a pure calcium sulfate dehydrate (gypsum) as control. Strontium-doped gypsum (Sr-gypsum) was obtained by mixing calcium sulfate hemihydrates powder and solutions of strontium nitrate followed by washing the specimens with distilled water for the removal of residual salts. Gypsum was the only phase found in the composition of both pure and Sr-gypsum meanwhile a shift into lower diffraction angles was observed in the x-ray diffraction patterns of doped specimens. The Sr-doped sampled exhibited higher compressive strength and lower solubility than pure gypsum. Microstructure of all gypsum specimens had been composed of many rod-like small crystals entangled to each others with more elongation and higher thickness in the cases of Sr-gypsum. EDXA pattern of Sr-gypsum showed the presence of calcium and sulfur ions as the main elements of gypsum as well as slight amount of strontium ion. A continuous release of strontium was observed from the Sr-gypsum after soaking in simulated body fluid for 14 days. Proliferation rate of cultured osteoblasts and higher alkaline phosphatase activity on doped samples was better compared to pure gypsum.

Keywords

Main Subjects

Biopolymers

References

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Iranian Journal of Biomedical Engineering

Physicochemical Properties And Cellular Responses Of Various Amounts Of Strontium-Doped Gypsum Bio Ceramics

References

References

Volume 3, Issue 2 - Serial Number 2
June 2009
Pages 99-109

Physicochemical Properties And Cellular Responses Of Various Amounts Of Strontium-Doped Gypsum Bio Ceramics

References

References

Volume 3, Issue 2 - Serial Number 2June 2009Pages 99-109

Volume 3, Issue 2 - Serial Number 2
June 2009
Pages 99-109