Determination Of Elastic Modulus Of Artery Wall By Modeling Of Artery Wall And Blood Flow

Maerefat, Mehdi; Khoushkar Shalmani, Asghar; Mokhtari Dizaji, Manije

doi:10.22041/ijbme.2007.13489

Document Type : Full Research Paper

Authors

¹ Associate professor, Mechanics Department, Engineering School, Tarbiat Modares University

² MS Mechanical Engineer, Engineering School, Tarbiat Modares University

³ Associate professor, Medical Physics Department, Medical School, Tarbiat Modares University

10.22041/ijbme.2007.13489

Abstract

Modeling of blood flow and arterial wall in large arteries such as carotid artery, using ultrasonic measurements, allows non-invasive evaluation of clinically interesting homodynamic variables. In this study, a nonlinear mathematical model for the pulsatile arterial flow is proposed using the approximation of “local flow” theory. The blood velocity profile, the pressure gradient and the elastic modulus can be calculated using the model by measuring instantaneous radius and center-line blood velocity. An original mathematical model of pressure gradient in a tapered and elastic tube, using center-line blood velocity, is presented. A Newtonian incompressible Navier-Stokes solver coupled with elastic or visco-elastic arterial wall model is developed to solve the equations of model. The results of modeling and simulation indicate that the approach can estimate the elastic modulus of arterial wall from ultrasonic data. There is a good agreement between the computed arterial wall elasticity and the measured one. The method presented is relatively simple to implement clinically and can be taken as a new diagnostic tool for detecting local vascular change.

Keywords

Main Subjects

References

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Iranian Journal of Biomedical Engineering

Determination Of Elastic Modulus Of Artery Wall By Modeling Of Artery Wall And Blood Flow

References

References

Volume 1, Issue 2 - Serial Number 2
June 2007
Pages 95-104

Determination Of Elastic Modulus Of Artery Wall By Modeling Of Artery Wall And Blood Flow

References

References

Volume 1, Issue 2 - Serial Number 2June 2007Pages 95-104

Volume 1, Issue 2 - Serial Number 2
June 2007
Pages 95-104