Volume 17 (2023)
Volume 16 (2022)
Volume 15 (2021)
Volume 14 (2020)
Volume 13 (2019)
Volume 12 (2018)
Volume 11 (2017)
Volume 10 (2016)
Volume 9 (2015)
Volume 8 (2014)
Volume 7 (2013)
Volume 6 (2012)
Volume 5 (2011)
Volume 4 (2010)
Volume 3 (2009)
Volume 2 (2008)
Volume 1 (2007)
Volume -2 (2005)
Volume -1 (2004)
Tissue Engineering
Analysis of the Effect of Shear Stress on the Differentiation Response of Mesenchymal Stem Cells in Multi-Layered Nanocomposite Scaffold for Bone-Cartilage Tissue Engineering Using Computational Methods

Sara Zadegan; Bahman Vahidi; Nooshin Haghighipour

Volume 16, Issue 3 , December 2022, , Pages 289-299

  Repairing osteochondral defects (OCD) remains a formidable challenge due to the high complexity of native osteochondral tissue and the limited self-repair capability of cartilage. In this regard, the development of osteochondral tissue engineering with scaffolds seeded with stem cells along with mechanical ...  Read More

Tissue Engineering
Simulation of Oxygen Distribution in a Scaffold with Microfluidic Channels for Tissue Engineering

Shahryar Ramezani Bajgiran; Maryam Saadatmand

Volume 11, Issue 3 , September 2017, , Pages 211-218

  Despite the advancements made in the tissue engineering, one of the obstacles in producing thick tissues is the means of oxygen transport to the deep layered cells of the engineered tissue and creating the network of veins inside the tissue. One way to overcome this problem is to create a microfluidic ...  Read More

Tissue Engineering
An Experimental Study on Alginate-Fibroin Hydrogels Mechanical Capability as Scaffolds for Vascular Tissue Engineering

Mehdi Navidbakhsh; Mehdi Sajjadi; Simzar Hosseinzade

Volume 11, Issue 1 , May 2017, , Pages 51-61

  Tissue engineering is a promising approach for developing viable alternative for current treatments of cardiovascular diseases such as autologous vessel and synthetic bypass graft transplantation. One of the major challenges in development of an applicable tissue engineered vessel is proper design of ...  Read More

Tissue Engineering
Morphological and Physiochemical Characteristics of biodegradable PLGA-Gelatin Scaffolds by Unidirectional Freezing Technique

Farnaz Ghorbani; Ali Zamanian; Hanie Noje Dehian

Volume 8, Issue 4 , February 2015, , Pages 399-409

  In this study, we fabricated 3-dimentional PLGA-gelatin scaffolds with aligned-oriented pores by freeze casting technique which is similar to Extra Cellular Matrix (ECM), and evaluated its effect on both physical and mechanical features. Dissolving synthetic (PLGA) and natural (Gelatin) polymers in common ...  Read More

Tissue Engineering
Numerical analysis of a single cultured mesenchymal stem cell under pressure stimulation using atomic force microscopy and finite element method

Zakieh Alihemmati; Bahman Vahidi; Nooshin Haghighipour

Volume 8, Issue 2 , June 2014, , Pages 135-149

  Body cells, including mesenchymal stem cells are subject to a lot of mechanical forces. The type and magnitude of these forces are different in different physiological and pathological conditions. They cause a wide variety of cell responses and are able to change metabolisms and functions of the cell. ...  Read More

Tissue Engineering
Domestic Construction of Soft Tissue Phantom for Validation Linear Quasi –Static Elastography

Zahra Saghaei Noosh Abadi; Atefe Aghajani; Mohammad Haghpanahi

Volume 7, Issue 1 , June 2013, , Pages 1-11

  We introduce how we may produce an experimental phantom for modeling the mechanical properties of soft tissue. Gelatin materials are used to construct the phantom. Our phantom comprises of two different types of tissue; tumor and background normal tissue. Weight ratio of the dry gelatin and deionized ...  Read More

Development and characterization of electrospun Mg-doped fluorapatite nanoparticles – PCL nanocomposite scaffolds for bone tissue engineering

Zeynab Fereshteh; Mohammad Hossein Fathi; Reza Mozaffarinia

Volume 6, Issue 3 , June 2012, , Pages 177-193

  The aim of this study was to prepare and characterize the novel poly (ε-caprolactone) / Mg-doped fluorapatite nanoparticles (PCL / nMg-FA) composite scaffolds by electrospinning method. The optimized composite was achieved by changing of electrospinning parameters such as solvent, polymer concentration, ...  Read More

Biomedical Image Processing / Medical Image Processing
Estimation Of Tissue Damage Using Exchange Rate Constant In Magnetic Resonance Imaging

Effat Yahaghi; Yashar Nohi; Amir Movafeghi; Hamid Soltanian Zadeh

Volume 4, Issue 1 , June 2010, , Pages 1-11

  Magnetic resonance imaging (MRI) is a non-ionizing method for identification and evaluation of soft tissue lesions. Perfusion MRI evaluates soft tissues by measuring changes in magnetization of water molecules due to a contrast agent. To this end, concentration curves in the plasma and tissue are estimated ...  Read More

Tissue Engineering
Evaluation of Electromagnetic Radiations (1.5 Tesla) Effect on Liver Functional Tests and Histometery of Liver in Adult Male Rats

Jafar Ai; Saeed Sarkar; Mohammad Ali Oghabian

Volume 4, Issue 2 , June 2010, , Pages 161-166

  Various reviews have shown that strong electromagnetic fields have negative effects on human health. This study focused on the effect of MRI radiation on liver functional test histometery of liver in adult male rats. For this purpose, we used an MRI device that could produce 1.5 T electromagnetic radiations, ...  Read More

Tissue Engineering
Modeling of Magnetic Field Effect on Nanofiber Jet Path in Electrospinning for Fabricating Optimum Tissue Engineering Scaffolds

Fateme Shamsi; Mohsen Janmaleki; Nasser Fatouraee

Volume 3, Issue 4 , June 2009, , Pages 265-274

  In this study a mechanism was modeled to control the jet path of nanofibers produced by electrospinning through inducing a magnetic field over the jet path. Firstly, a model was developed for the jet path in which the fibers composed of a series of viscoelastic segments. Considering the mass and momentum ...  Read More

Biomechanics of Bone / Bone Biomechanics
Preparation of Nanocomposite Gelatin/Apatite Scaffold through a Biomimetic Method

Mahmoud Azami; Fathollah Moztarzadeh; Mohammad Rabiee

Volume 3, Issue 4 , June 2009, , Pages 275-284

  During past decade, using biomimetic approaches has received much attention by scientists in the field of tissue substitutes preparation. These approaches have been employed for synthesis of bone tissue engineering scaffolds in the case of either materials or synthesis methods. In this study, an apatite ...  Read More

Biomechanics of Bone / Bone Biomechanics
Investigation of Human Mesenchymal Stem Cells Adhesion and Diffusion into Poly (lactic-co-glycolic acid)/Hydroxyapatite Porous Scaffold Coated with a Biodegradable Triblock Copolymer

Masoume Haghbin Nazarpak; Farzane Pourasgari; Mohammad Nabi Sarbolouki

Volume 3, Issue 4 , June 2009, , Pages 291-298

  The scaffolds for bone tissue engineering should consider the functional requirements: porosity, biocompatibility, and biodegradability. In this study, porous Poly (lactic-co-glycolic acid)/Hydroxyapatite composites were prepared with different weight ratios. Porous samples were fabricated by freeze-extraction ...  Read More

Tissue Engineering
Modeling the Effects of Biomechanical Factors on the Deformability of Metastatic Cancer Cells

Mehdi Navidbakhsh; Milade Jafarnejad

Volume 3, Issue 4 , June 2009, , Pages 299-306

  The cancer changes the cytoskeleton of the cells .This change has some effects on the cell mechanobiology and will lead to some changes in the deformability of the cells. The moving ability of the cancer cells would be more than healthy cells. Thus, they can migrate through the tissue in human body. ...  Read More

Tissue Engineering
Effect of Static Stretch on Alignment of Human Mesenchymal Stem Cells

Mohsen Rabbani; Mohammad Tafazzoli Shadpour; Zahra Goli Malekabadi; Mohsen Janmaleki; Mohammad Taghi Khorasani; Mohammad Ali Shokrgozar

Volume 3, Issue 4 , June 2009, , Pages 307-314

  Vital function of the cell is correlated with the mechanical loads that the cell experiences. The cell shape and morphology are also related to its mechanical environments. Different methods have been proposed to obtain cell groups with the same morphology and alignment which considered desirable features ...  Read More

Tissue Engineering
Investigation and Characterization of Agarose-Gelatin Blend Hydrogel, as a Cellular Carrier Substrate for Cell Therapy Application

Rana Imani; Parisa Rahnama Moshtaq; Shahriar Hojati Emami; Sasan Jalili; Ali Mohammad Sharifi

Volume 3, Issue 4 , June 2009, , Pages 315-324

  Cell therapy based on cell encapsulation technology holds out the promise of the treatment of many diseases. The technology of cell encapsulation represents a strategy in which cells that secrete therapeutic products are immobilized and immunoprotected within polymeric and biocompatible carriers. Hydrogels ...  Read More

Tissue Engineering
Triphasic Finite Element Modeling of Intervertebral Discs for Biomechanical Studies in Tissue Engineering

Mohammad Haghpanahi; Mohammad Nikkhoo; Habibollah Peirovi

Volume 2, Issue 1 , June 2008, , Pages 47-56

  According to mechanobilogical studies as an infrastructure for tissue engineering researches, this paper presents a triphasic finite element modeling of intervertebral discs such a hydrated porous soft tissue. First, the governmental equations were derived on the basis of the laws of continuum mechanics. ...  Read More

Biomechanics of Bone / Bone Biomechanics
Effect Of Liquid Phase Concentration On Setting Time And Compression Strength Of Hydroxyapatite Bone Cement

Seyed Mahmoud Rabiei; Fathollah Moztarzadeh; Mehran Solati Hashjin; Saeed Hesaraki

Volume 1, Issue 2 , June 2007, , Pages 105-110

  In this research, the influence of NaH2PO4.2H2O with different concentrations on setting time and compressive strength of bone cement based on hydroxyapatite was investigated. Hydroxyapatite cement is of calcium phosphate bone cements, which can be considered as the best substitute for hard tissues. ...  Read More

Tissue Engineering
Studying The Biomechanical Behavior Of Brain Tissue Comparing Elastic And Hyperelastic Models

Farhad Farmanzad; Siamak Najarian; Mohammad Reza Eslami; Amir Saeed Seddighi

Volume 1, Issue 4 , June 2007, , Pages 281-288

  Two different types of computer modeling, i.e., the elastic and hyperelastic plane strain models were employed and compared with each other. Using finite element analysis, we determined a suitable model for describing the biomechanical behavior of the brain, especially the deformation and displacement ...  Read More

Biomechanics of Bone / Bone Biomechanics
Synthesis And Dissolution Kinetics In A Simulated Bone Resorption Medium Of Amorphous Carbonated Calcium Phosphates

Abdorreza Sheikh Mehdi Mesgar; Zahra Mohammadi; Fathollah Moztarzadeh; Mahtab Ashrafi Khouzani; Zeinab Sadat Mohammadi

Volume 1, Issue 1 , June 2007, , Pages 39-51

  Amorphous carbonated calcium phosphates (ACCPs) with different carbonate contents and Ca/P ratios were reproducible synthesized by the reaction parameters as low temperature, high pH value, using initial solutions of calcium and phosphate at low concentrations, and various amounts of carbonate, as well ...  Read More

Tissue Engineering
Effect Of Continuous, Repeated And Intermittent Pressure On The Biomechanical And Histological Characteristics Of Guinea Pig Skin

Giti Torkamaan; Ali Fallah; Mahmoud Mofid; Sedighe Ghiasi; Ghadam Ali Talebi

Volume 1, Issue 3 , June 2007, , Pages 215-225

  In this study 22 male Guinea Pigs, 4-6 months old, weighting 400-450 g were used. A computer controlled indentor system was used to apply a controlled pressure. The applied pressure was 291 mmHg for 3 hours over the trochanter region of animal hind limb. The animals were divided in three groups; in group ...  Read More

Bacterial Synthesis Of Nano-Crystalline Hydroxyapatite

Babak Mostaghasi; Mohammad Hossein Fathi; Mahmoud Sheikh Zeinaddin; Sabihe Soleimanianzad

Volume 1, Issue 2 , June 2007, , Pages 137-146

  Hydroxyapatite (HA) is a well known candidate for many applications in dentistry and medicine such as bone replacement and regeneration and coatings for medical implants. Nano-crystalline HA exhibits improved mechanical properties and biocompatibility. To optimize the benefits of nano-sized precursors, ...  Read More

Tissue Engineering
Synthesis Of Amorphous Calcium Phosphate And Its Solubility Behavior In Simulated Osteoclastic Activity Conditions

Abdorreza Sheikh Mehdi Mesgar; Zahra Mohammadi

Volume -1, Issue 1 , June 2004, , Pages 47-55

  The conditions for synthesis of amorphous calcium phosphates (ACPs) according to the crystallization principles were described. By selecting reaction parameters correctly (low temperature, high pH, immediate removing of water and using solutions containing calcium cations and phosphate anions at low ...  Read More

Tissue Engineering
Fabrication Of A Porous Composite Scaffold For Bone Tissue Engineering Based On Gelatin And Hydroxyapatite, Part I: Cell Culture Results

Karim Asgarzadeh Tabrizi; Fariba Ourang

Volume -1, Issue 1 , June 2004, , Pages 57-64

  Gelatin is a protein which is derived from the organic constituent of bone (collagen). Combination of this protein with the inorganic constituent of bone (hydroxyapatite) may provide closer properties to the natural bone. In this study, a biodegradable composite scaffold based on gelatin and hydroxyapatite ...  Read More

Tissue Engineering
Skin Response To Applied Pressure In Model Of Guinea Pig

Giti Torkamaan; Ali Akbar Sharafi; Ali Fallah; Hamid Reza Katouzian; Mahmoud Mofid

Volume -1, Issue 1 , June 2004, , Pages 93-100

  Pressure ulcers are areas of tissue necrosis that tend to develop when tissue is compressed between a bony prominence and an external surface. Normal structure and physiological function of tissue viability are recognized but mechanism of tissue breakdown is unknown. In this study, an attempt has been ...  Read More