Volume 17 (2023)
Volume 16 (2022)
Volume 15 (2021)
Volume 14 (2020)
Volume 13 (2019)
Volume 12 (2018)
Volume 11 (2017)
Volume 10 (2016)
Volume 9 (2015)
Volume 8 (2014)
Volume 7 (2013)
Volume 6 (2012)
Volume 5 (2011)
Volume 4 (2010)
Volume 3 (2009)
Volume 2 (2008)
Volume 1 (2007)
Volume -2 (2005)
Volume -1 (2004)
Biological Computer Modeling / Biological Computer Simulation
A developed computational model of oxygen diffusion caused by angiogenesis in a cancer tissue

mohamood borzouei; modjtaba emadi-baygi; mohammad mardaani; hasan rabani

Volume 17, Issue 1 , May 2023, , Pages 51-60

  It is critical for developing treatment strategies to investigate and analyze the growth dynamics and changes of invasive tumors in response to various microenvironmental conditions. When a tumor reaches its maximum amount of non-vascular growth, its cells compete for more food and oxygen sources, triggering ...  Read More

Biological Computer Modeling / Biological Computer Simulation
A Mathematical Model of Tumor-Immune System with Fuzzy Parameters

Sajad Shafiekhani; Amin Mashayekhi Shams; Seyed Yashar Banihashem; Nematollah Gheibi; Amir Homayoun Jafari

Volume 14, Issue 1 , May 2020, , Pages 55-67

  According to cancer’s global statistics, there will be 27.5 million new cases of cancer each year by 2040, therefore, it is crucial to achieve a deeper understanding of the cancer progression mechanisems and immune system functions in response to it. Nowadays, computational models are widely used ...  Read More

Biofluid Mechanics / Biofluids
Computational Simulation of Airflow with Aerosols in Distal Parts of a Human Respiratory System: Investigating the Effects of Gravity

Mohammad Ahmadi Alashti; Bahman Vahidi; Mahtab Ebad

Volume 13, Issue 1 , April 2019, , Pages 1-15

  The large surface area of the lung with its thin air-blood barrier is exposed to particles in the inhaled air. In this condition, if the inhaled pollutant aerosols are toxic, the particle-lung interaction may cause serious hazards and injuries on human’s health. On the otherhand, these interactions ...  Read More

Biological Computer Modeling / Biological Computer Simulation
Modeling Obstructive Sleep Apnea using Dynamical Phase Transition

Somayeh Raiesdana

Volume 12, Issue 3 , November 2018, , Pages 249-263

  Sleep is an essential process to maintain and improve human activities, while many details related to sleep are still not well understood. Decreased or fragmented sleep is a health risk that might result in heart disease or diabetes on one hand and degradation of consciousness and cognition on the other ...  Read More

Biological Computer Modeling / Biological Computer Simulation
Modeling Two Delay System of Insulin-Glucose based on Noninvasive Continuous Measurement

Reza Vosoughi; Armin Allahverdy; Sajjad Shafiekhani; Amir Homayoun Jafari

Volume 11, Issue 4 , February 2018, , Pages 291-301

  In recent decades, due to the increased prevalence of diabetes and its chronic complications, glucose measurement, modeling of glucose-insulin system and glucose control have been especially important. Since the type I diabetes does not secrete insulin, cells do not absorb glucose, and thus the blood ...  Read More

Biological Computer Modeling / Biological Computer Simulation
Molecular Dynamics Simulation of PASylated G-CSF and Proposing a Modified PAS String Sequence in order to Improve Drug’s Properties

Abbas Gholami; Amir Shamloo

Volume 11, Issue 4 , February 2018, , Pages 303-311

  PASylation is a new and effective way to increase the half-life of pharmaceutical proteins. This method is an alternative of PEGylaion and uses the natural polymers of Proline, Alanine, and Serine (PAS) amino acids in its structure. In this paper, we have studied the pharmacokinetic properties of PASylated ...  Read More

Biological Computer Modeling / Biological Computer Simulation
A New Method for Slowing Down Avascular Tumor Growth

Seyed Hojat Sabzpoushan; Fateme Pourhasanzade

Volume 11, Issue 1 , May 2017, , Pages 1-18

  In this paper, a new method is proposed for slowing down avascular tumor growth. Our method is established on an agent based avascular tumor growth model (ABM). The model is based on biological assumptions with regard to the immune system interactions. The model parameters are fitted in compatability ...  Read More

Biological Computer Modeling / Biological Computer Simulation
Dynamical Analysis and Bifurcations of Jansen-Rit's Neural-Mass Model and Its Application in Describing Epileptic Seizures

Mohammad Reza Khodabakhshi; Amir Hossein Davaie Markazi

Volume 11, Issue 1 , May 2017, , Pages 63-81

  Nowadays, with technological advancements and increasing computing power, the use of mathematical models to describe the functioning of the brain in normal and abnormal manners, especially the study of the formation causes and methods of controlling and treating some nervous system diseases, such as ...  Read More

Biological Computer Modeling / Biological Computer Simulation
A Multiscale Hybrid Cellular Automata Model of Tumor Growth: The Impact of Nutrient and Acidity on Tumor Growth

Fateme Pourhasan Zade; Seyed Hojat Sabzpoushan; Ali Mohammad Alizade; Ebrahim Esmati

Volume 10, Issue 2 , August 2016, , Pages 99-112

  Cancer is the third leading cause of death in Iran after cardiac diseases and car accidents. Mathematical and computational models are great help to better understand cancer related phenomena. It may even improve common therapies or introduce new therapies. In this paper, a new multiscale cellular automata ...  Read More

Biological Computer Modeling / Biological Computer Simulation
Modeling and Simulation of Vascular Tumor Growth

Mahdie Roghani Yazdi; Nadia Naghavi; Faride Sadat Hosseini

Volume 9, Issue 2 , July 2015, , Pages 143-161

  A tumor cannot grow more than a few millimeters without a blood supply (avascular tumor), and for further growth it must initiate angiogenesis process. A vascularized tumor, which is permeated with blood vessels, rapidly increases in mass because of the new source of oxygen. In this study, a discrete ...  Read More

Biological Computer Modeling / Biological Computer Simulation
Bifurcation Analysis of Early Afterdepolarizations in a Ventricular Cell Model

Seyed Hojat Sabzpoushan; Niloofar Shahidi; Azadeh Ghajarjazy

Volume 9, Issue 4 , February 2015, , Pages 351-360

  Abnormal oscillations of ventricular cell action potential can lead to cardiac arrhythmias. Early afterdepolarizations (EADs) is one kind of these oscillations that have been widely studied in the field of cardiac arrhythmias diagnosis and therapies. Nowadays although ventricular cell models have been ...  Read More

Biological Computer Modeling / Biological Computer Simulation
Optimal Feature Selection in Biologically Inspired Model for Object Recognition Using Mutual Information Maximisation

Mohammad Jazlaeiyan; Hadi Shahriar Shahhoseini

Volume 8, Issue 4 , February 2015, , Pages 371-383

  Human visual system operates superior than best machine vision systems in object recognition. So, researchers in machine vision and neuroscience try to model human visual system in order to employ it in machine. HMAX is one of the best operating models in this area. It is based on the function of brain ...  Read More

Biomechanics of Bone / Bone Biomechanics
Design and Biomechanical Study of the First Iranian Cervical Cage using Finite Element Analyses

Mohammad Nikkhoo; Ali Tahassori; Mohammad Haghpanahi

Volume 8, Issue 3 , September 2014, , Pages 203-212

  To develop the advanced technologies in medical device industry, design and manufacturing of cervical cage was performed in Iran for the first time. This research-based industrial project should be accomplished based on precise biomechanical studies and mechanical tests. Hence, this study presents the ...  Read More

Cardiovascular Biomechanics
Measurement of mechanical properties of human saphenous vein using an inflation experiment

Farzad Forouzandeh; Mahdie Haji-Bozorgi; Behrooz Meshkat; Nasser Fatouraee

Volume 8, Issue 3 , September 2014, , Pages 241-248

  Coronary Artery Diseases are one of the main reasonsof mortality. When these arteries occlude, usually a CoronaryArtery Bypass Graft (CABG) surgery is performed. Sine humanSaphenous Veins (SV) is used for CABG, they are of interest forresearchers. In this study human SV samples undergo inflationtest, ...  Read More

Biological Computer Modeling / Biological Computer Simulation
Mathematical Modeling and Simulation in order to Evaluation of the Nanoparticle Size in the Magnetic Drug Targeting System

Gelare Valizadeh; Fateme Fatemi; Mahmoud Shahabadi; Mohammad Ali Oghabian; Majid Pouladian

Volume 8, Issue 2 , June 2014, , Pages 125-133

  MTDDS is an innovative treatment modality to completely tumor remission with no negative side effect. In this method functionalize magnetic nanoparticles are designed as the drug carrier to get the specific target in the body. Anticancer agents are bounded to magnetite nanoparticles with biocompatible ...  Read More

Tissue Engineering
Numerical analysis of a single cultured mesenchymal stem cell under pressure stimulation using atomic force microscopy and finite element method

Zakieh Alihemmati; Bahman Vahidi; Nooshin Haghighipour

Volume 8, Issue 2 , June 2014, , Pages 135-149

  Body cells, including mesenchymal stem cells are subject to a lot of mechanical forces. The type and magnitude of these forces are different in different physiological and pathological conditions. They cause a wide variety of cell responses and are able to change metabolisms and functions of the cell. ...  Read More

A Combined Wavelet Based Mesh Free-Finite Element Method for Solving the Forward Problem in Magnetic Induction Tomography

Mohammad Reza Yousefi; Reza Jafari; Hamid Abrishami Moghaddam

Volume 8, Issue 1 , March 2014, , Pages 69-86

  In this paper, a combined wavelet based mesh free method has been presented to solve the forward problem in magnetic induction tomography (MIT). Being a non-contact safe imaging technique, MIT has been an appropriate method for noninvasive industrial and medical imaging. In this imaging method, a primary ...  Read More

Continuum model of actin-myosin flow

Mohammad Reza Nikmaneshi; Bahar Firoozabadi; Mohammad Saeid Saeidi

Volume 7, Issue 2 , June 2013, , Pages 97-105

  The front part of a cell is divided to two regions called lamellum and lamellipodium (lamellipodial). Internal flows in this part plays an essential role for cell migration. Indeed, there are many protein filaments called actin in lamellum and lamellipodium, which induce the cell motion with polymerization ...  Read More

Robotic Surgery / Robot-Assisted Surgery
A New Hybrid Algorithm for Simulation of Cutting Soft Tissue Using Finite Element Method

Marzie Saeidirad; Heidar Ali Talebi; Mohammad Zareinejad; Mohammad Reza Dehghan

Volume 7, Issue 4 , June 2013, , Pages 287-296

  Computationally fast biomechanical models are required to present the actual behavior of soft tissue in real-time simulation. These models are applied in medical diagnosis, surgical planning and training. One of the challenges in the surgical simulation is soft tissue cutting that requires topology changes ...  Read More

Biological Computer Modeling / Biological Computer Simulation
Four-dimensional modeling of GBM brain tumor growth using cellular automata

Seyed Hojat Sabzpoushan; Fateme Pourhasan Zadeh; Zohre Agin

Volume 7, Issue 1 , June 2013, , Pages 65-73

  A great number of people are diagnosed with a brain tumor, annually. Glioblastoma multiform (GBM) is the most common and deadliest malignant primary brain tumor. Therefore, the study of the growth of GBM is one of the issues considered by researchers. Many mathematical models to simulate the growth of ...  Read More

Biological Computer Modeling / Biological Computer Simulation
Computational Modeling of Micro-particle Deposition in the Second Generation of Bronchial tree (of Human Pulmonary System)

Hosein Ghasemi; Mohammad Saeid Saeidi; Bahar Firoozabadi

Volume 7, Issue 3 , June 2013, , Pages 255-264

  Knowledge regarding particle deposition processes in the pulmonary system is important in aerosol therapy and inhalation toxicology applications. The present work describes a computational model of human lung airway consisting of the three-generation pathway from the trachea down to segmental bronchi. ...  Read More

Orthotics & Prosthesis
Comparison of Friction Force at Contact Surfaces between the Arch Wire and the Slot of Orthodontic Bracket: a Finite Element Method

Mostafa Lashgari; Farzan Ghalichi; Behnam Mirzakouchaki

Volume 7, Issue 4 , June 2013, , Pages 341-349

  Orthodontic specialists interest in study of tooth movement mechanic, such as the relationship between applied force and the rate of tooth movement in orthodontic treatment. It is because of the complexity and variety of factors that can affect orthodontic treatment. The friction force at the contact ...  Read More

Biomedical Signal Processing / Medical Signal Processing / Biosignal Processing
Autoregressive Modeling of the Photoplethysmogram AC Signal Amplitude Changes after Flow-Mediated Dilation in Healthy and Diabetic Subjects

Mina Amiri; Edmond Zahedi; Fereydoun Behnia

Volume 7, Issue 1 , June 2013, , Pages 85-95

  It is proved that the endothelial (artery inner lumen cells) function is associated with cardiovascular risk factors. Among all the common non-invasive methods employed in the research setting for assessing endothelial function, flow-mediated dilation is the most widely used one. This technique measures ...  Read More

Experimental essay of peristaltic fluid flow in the biologic tube

Behzad Seyfi; Hosein Mansourinejad; Bahman Vahidi; Nasser Fatouraee

Volume 6, Issue 3 , June 2012, , Pages 169-175

  Peristaltic flow is one of the important mechanisms of fluid transmission. In addition to the divers engineering applications, this mechanism plays an important role in biological organs such as digestion system and urine excretion. In this paper, urine bolus transportation in ureter has been investigated ...  Read More

Fluid-Structure Interaction in Biological Media / FSI
Effects of Cardiac Motion on Coronary Artery Flow rate

Alireza Hashemi Fard; Nasser Fatouraee

Volume 5, Issue 1 , June 2011, , Pages 1-12

  The heart muscle is supplied via the coronary arteries. The coronary arteries are deformed in each cardiac cycle by the contraction of the myocardium. The aim of this work was to investigate the effects of physiologically idealized cardiac-induced motion on flow rate in human left coronary arteries. ...  Read More