نشریه علمی مهندسی پزشکی زیستی
Iranian Journal of Biomedical Engineering (IJBME)

تحلیل همودینامیک دریچه‌ی آئورت از طریق مدل‌سازی محاسباتی به روش لاگرانژی اویلری اختیاری

نوع مقاله : مقاله کامل پژوهشی

نویسندگان

علیرضا هاشمی‌فرد 1
ناصر فتورائی 2
ملیکه نبئی 3

1 دانشجوی دکتری، آزمایشگاه تحقیقاتی دینامیک سیالات بیولوژیکی، دانشکده‌ی مهندسی پزشکی، دانشگاه صنعتی امیرکبیر، تهران، ایران

2 دانشیار، آزمایشگاه تحقیقاتی دینامیک سیالات بیولوژیکی، دانشکده‌ی مهندسی پزشکی، دانشگاه صنعتی امیرکبیر، تهران، ایران

3 استادیار، آزمایشگاه تحقیقاتی دینامیک سیالات بیولوژیکی، دانشکده‌ی مهندسی پزشکی، دانشگاه صنعتی امیرکبیر، تهران، ایران

https://doi.org/10.22041/ijbme.2024.2021080.1881
چکیده
وظیفه‌ی مهم و اساسی دریچه‌ی آئورت، جلوگیری از بازگشت خون از شریان آئورت به بطن چپ است. باز شدن و بسته شدن به موقع و دقیق دریچه‌ی آئورت می‌تواند به تامین فشار خون مناسب و برون‌ده قلبی مطلوب کمک کند. به همین دلیل شبیه‌سازی عمل‌کرد دریچه‌ی آئورت می‌تواند به شناخت نحوه‌ی عمل‌کرد اجزای آن کمک کرده و محدوده‌ی تغییرات کمیت‌های مرتبط با همودینامیک دریچه‌ی آئورت و ارتباط آن‌ها را مشخص سازد. بر این اساس در این پژوهش مدل محاسباتی دریچه‌ی آئورت به روش لاگرانژی اویلری اختیاری حل شده و نمودارهای فشار بطن چپ و اختلاف فشار بطن چپ نسبت به شریان آئورت، سطح باز بین لت‌های دریچه، میزان جریان خون، منحنی فشار به حجم بطن چپ، انرژی بطن چپ، دانسیته‌ی انرژی سینماتیکی و اتلاف لزجی، مقاومت دریچه، اختلاف فشار سیال در دو طرف سطح لت‌ها و اختلاف فشار لحظه‌ای محور طولی دریچه نسبت به فشار شریان آئورت گزارش شده و بر اساس آن فرایند باز شدن و بسته شدن دریچه‌ی آئورت تحلیل شده است. حرکت لت‌ها به عنوان جابه‌جایی مرز جامد در روش تعامل سیال و جامد، شبکه‌ی محاسباتی سیال را دستخوش جابه‌جایی و تغییر کرده که با توالی بازسازی شبکه‌ی محاسباتی سیال تصحیح می‌شود. در طی این فرایند مشکلاتی رخ می‌دهد که جزئیات و چگونگی پرهیز از بروز آن در این مقاله به تفصیل بیان شده است.

کلیدواژه‌ها

سینوس والسالوا
تعامل سیال و جامد
بازسازی شبکه‌ی محاسباتی
فشار بطن چپ
سطح باز دریچه
انرژی سینماتیکی
اتلاف لزجی
مقاومت دریچه

موضوعات

عنوان مقاله English

Aortic Valve Hemodynamic Analysis through Computational Modeling ALE

نویسندگان English

Alireza Hashemifard 1
Nasser Fatouraee 2
Malikeh Nabaei 3
1 Ph.D. Student, Biomedical Engineering Faculty, Amirkabir University of Technology, Tehran, Iran
2 Associate Professor, Biomedical Engineering Faculty, Amirkabir University of Technology, Tehran, Iran
3 Assistant Professor, Biomedical Engineering Faculty, Amirkabir University of Technology, Tehran, Iran
چکیده English

The crucial responsibility of the aortic valve is to prevent returning of blood flow from the aorta back to the left ventricle. In-time and accurate opening and closing of the aortic valve can effectively produce the desired blood pressure and cardiac output. For this reason, aortic valve simulation can identify changes related to aortic valve hemodynamics and their relationship. Diagrams of the left ventricular pressure, the left ventricular pressure difference relative to the aortic artery, GOA, blood flow, the left ventricle pressure-to-volume, the left ventricular energy, kinematic energy density, viscous dissipation, valve resistance, fluid pressure difference in two the surface side of the leaflets, and the momentary pressure difference of the longitudinal axis of the aortic valve compared to the pressure of the aortic artery are reported in this research and based on these, the process of opening and closing of the aortic valve is analyzed using numerical methods named ALE. The moving of the aortic leaflet as the displacement of the solid boundary in the fluid-solid interaction method causes the fluid mesh to undergo displacement and change, which is repaired by the sequence of re-meshing in the fluid domain. In this process, problems occur, the details of which and the resolving method are explained in detail.

کلیدواژه‌ها English

Sinus Valsalva
FSI
Re-Meshing
Left Ventricle Pressure
GOA
Kinetic Energy
Viscous Dissipation
Valve Resistance
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نشریه علمی مهندسی پزشکی زیستی
دوره 17، شماره 3
پاییز 1402
صفحه 219-233

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  • تاریخ دریافت 03 بهمن 1402
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